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  • Theobromine

    Theobromine chemical structure
    Theobromine

    3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione
    CAS number
    83-67-0
    ATC code
    C03BD01 and R03DA07
    Chemical formula C7H8N4O2
    Molecular weight 180.166
    Bioavailability  ?
    Metabolism  ?
    Elimination half-life  ?
    Excretion  ?
    Pregnancy category  ?
    Legal status Uncontrolled substance
    Routes of administration  ?

    Theobromine is a bitter alkaloid of the methylxanthine family, which also includes the similar compounds theophylline and caffeine. It is known to induce mutations in bacteria and lower eukaryotes, but does not seem to cause mutations in higher eukaryotes, such as humans. Despite its name, the compound contains no bromine.

    Theobromine is a chemical stimulant frequently confused with caffeine, but has very different effects on the human body. It is a mild, lasting stimulant with a mood improving effect. In medicine, it is used as a diuretic, vasodilator, and myocardial stimulant.

    Theobromine is the primary alkaloid found in cocoa and chocolate (Theobroma cacao is the scientific name of the cacao tree). Its presence is one of the causes for chocolate's mood-elevating effects. In chocolate, theobromine exists in doses that are safe for humans to consume in large quantities, but can be lethal for animals such as dogs and horses, as they metabolize theobromine more slowly.

    Scientists have recently discovered that theobromine has an antitussive effect superior to codeine by suppressing vagus nerve activity. [1]

    Alternate names are: Riddospas, Riddovydrin, Santheose, Seominal, Theobrominum, Theoguardenal, Theominal and Théoxalvose.

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